Investigating metabolic pathways in disease
The rising prevalence of obesity worldwide and its associated metabolic derangements, such as type 2 diabetes mellitus and cardiovascular disease, pose an enormous public health challenge. The primary focus of the Lo lab is to understand the fundamental molecular mechanisms of metabolic diseases such as diabetes, obesity and cardiovascular disease with the ultimate goal of developing novel treatments directed against them. We span the gamut of model systems from studying protein function in a test tube to performing in vitro cell culture to generating new mouse models and to analyzing human samples in disease states.
To understand the fundamental molecular mechanisms of metabolic diseases we are currently taking multiple approaches such as adipose biology and pancreatic islet physiology.
The Lo lab is comprised of post-doctoral fellows, PhD students, medical students, and research technicians who are dedicated to performing high-quality research.
Keep up to date with the latest publications, conferences, awards, and other exciting developments in the Lo lab.